Human stomach alcohol and aldehyde dehydrogenases: comparison of expression pattern and activities in alimentary tract.

@article{Yin1997HumanSA,
  title={Human stomach alcohol and aldehyde dehydrogenases: comparison of expression pattern and activities in alimentary tract.},
  author={Shih-Jiun Yin and Chun Sheng Liao and Cindy W. Wu and Tracy T Li and L. L. Chen and Ching Lung Lai and Twee Y. Tsao},
  journal={Gastroenterology},
  year={1997},
  volume={112 3},
  pages={
          766-75
        }
}
BACKGROUND & AIMS Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are the major enzymes responsible for ethanol metabolism in humans. The human stomach has been documented to be involved in the metabolism of first-passed alcohol. The aim of this study was to determine ethanol-metabolizing activities in the stomach with regard to sex, age, enzyme pattern, and polymorphism. METHODS A total of 209 surgical gastric mucosal specimens were investigated. The expression patterns of ADH… CONTINUE READING

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