Human steroidogenesis: implications for controlled ovarian stimulation with exogenous gonadotropins

@inproceedings{Andersen2014HumanSI,
  title={Human steroidogenesis: implications for controlled ovarian stimulation with exogenous gonadotropins},
  author={Claus Y. Andersen and Diego Ezcurra},
  booktitle={Reproductive biology and endocrinology : RB&E},
  year={2014}
}
In the menstrual cycle, the mid-cycle surge of gonadotropins (both luteinising hormone [LH] and follicle-stimulating hormone [FSH]) signals the initiation of the periovulatory interval, during which the follicle augments progesterone production and begins to luteinise, ultimately leading to the rupture of the follicle wall and the release of an oocyte. The administration of gonadotropins in controlled ovarian stimulation (COS) leads to supraphysiological steroid concentrations of a very… CONTINUE READING
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