# Human sperm accumulation near surfaces: a simulation study

@article{Smith2009HumanSA, title={Human sperm accumulation near surfaces: a simulation study}, author={Douglas J. Smith and Eamonn A. Gaffney and John R. Blake and Jackson C. Kirkman-Brown}, journal={Journal of Fluid Mechanics}, year={2009}, volume={621}, pages={289 - 320} }

A hybrid boundary integral/slender body algorithm for modelling flagellar cell motility is presented. The algorithm uses the boundary element method to represent the ‘wedge-shaped’ head of the human sperm cell and a slender body theory representation of the flagellum. The head morphology is specified carefully due to its significant effect on the force and torque balance and hence movement of the free-swimming cell. The technique is used to investigate the mechanisms for the accumulation of…

## 193 Citations

A study of spermatozoan swimming stability near a surface.

- Biology, MedicineJournal of theoretical biology
- 2014

The predicted sensitivity of the accumulation height of swimming sperm to the beat pattern wavenumber is sufficient to suggest the possibility that the limited focal depth of typical microscopy studies analysing flagellar patterns with a fixed focal plane may inadvertently bias the wavenumbers of the sperm that are observed.

SIMULATION OF SPERM SWIMMING IN AMBIENT FLUID

- Biology
- 2009

Sperm swimming in a viscous fluid is simulated numerically by the immersed boundary method and both the familiar travelling-wave and the asymmetric parabola flagellum beatings are simulated.

Hydrodynamics of sperm cells near surfaces.

- Biology, MedicineBiophysical journal
- 2010

The mesoscale hydrodynamics simulations in combination with a mechanical sperm model provide a theoretical framework that explains several distinct swimming behaviors of sperm near and far from a wall and suggests a mechanism by which sperm navigate in a chemical gradient via a change of their shape.

Two-dimensional slither swimming of sperm within a micrometre of a surface

- Biology, MedicineNature communications
- 2015

Using total internal reflection fluorescence microscopy, motile human and bull sperm are selectively imaged located within one micron of a surface, revealing a distinct two-dimensional ‘slither' swimming mode whereby the full cell length is confined within 1 μm of asurface.

Hydrodynamic study of sperm swimming near a wall based on the immersed boundary-lattice Boltzmann method

- Physics
- 2020

This paper presents a numerical study on a sperm swimming in a viscous fluid by using an immersed boundary-lattice Boltzmann method (IB-LBM). The sperm is modeled simply by integrating a slender tail…

Surface accumulation of spermatozoa: a fluid dynamic phenomenon

- Physics
- 2010

Recent mathematical fluid dynamics models have shed light into an outstanding problem in reproductive biology: why do spermatozoa cells show a 'preference' for swimming near to surfaces? In this…

An ALE-based finite element model of flagellar motion driven by beating waves: A parametric study

- Physics, Computer ScienceComput. Biol. Medicine
- 2015

By taking non-Newtonian fluids into account, a computational model of flagellar motility is presented using the finite element method and it is found that the model microorganism swims much more efficiently in shear-thinning fluids.

High-precision tracking of sperm swimming fine structure provides strong test of resistive force theory

- Mathematics, MedicineJournal of Experimental Biology
- 2010

This theory accurately predicts the complex trajectories of sperm cells from the detailed shape of their flagellar beat across different time scales, consistent with quantitative predictions of resistive force theory.

Human sperm swimming in a high viscosity mucus analogue.

- Physics, MedicineJournal of theoretical biology
- 2018

Signs are observed that the core feature in explaining the effectiveness of sperm swimming in high viscosity media is the loss of cell yawing, which is related with a greater density of regularised point force singularities along the axis of symmetry of the flagellar beat to represent the flow field.

Modelling bacterial behaviour close to a no-slip plane boundary: the influence of bacterial geometry

- BiologyProceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
- 2010

Using a boundary-element method used to model the hydrodynamics of a bacterium propelled by a single helical flagellum, it is demonstrated that hydrodynamic forces may trap the bacterium in a stable, circular orbit near the boundary, leading to the empirical observable surface accumulation of bacteria.

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