Human small G proteins, ObgH1, and ObgH2, participate in the maintenance of mitochondria and nucleolar architectures.

@article{Hirano2006HumanSG,
  title={Human small G proteins, ObgH1, and ObgH2, participate in the maintenance of mitochondria and nucleolar architectures.},
  author={Yasuhiro Hirano and Ryosuke L. Ohniwa and Chieko Wada and Shige H Yoshimura and Kunio Takeyasu},
  journal={Genes to cells : devoted to molecular & cellular mechanisms},
  year={2006},
  volume={11 11},
  pages={1295-304}
}
The Obg subfamily protein is one of the P-loop small G proteins and is highly conserved in many organisms from bacteria to human. Two obg genes, obgH1 and obgH2, exist in the human genome. Both ObgH1 and ObgH2 showed similar GTPase activities (0.014 +/- 0.005 and 0.010 +/- 0.002/min for ObgH1 and ObgH2, respectively) to those of the bacterial Obg proteins and complemented the Obg function in Escherichia coli ribosome maturation, suggesting that the functions of Obg proteins are well conserved… CONTINUE READING