Human skin model for mimic dermal studies in pathology with a clinical implication in pressure ulcers.

@article{Cristbal2018HumanSM,
  title={Human skin model for mimic dermal studies in pathology with a clinical implication in pressure ulcers.},
  author={Lara Crist{\'o}bal and Miguel Angel Ram{\'i}rez Ortega and {\'A}ngel As{\'u}nsolo and Beatriz Romero and Melchor {\'A}lvarez-Mon and Julia Buj{\'a}n and Andr{\'e}s A Maldonado and Natalio Garc{\'i}a-Honduvilla},
  journal={Histology and histopathology},
  year={2018},
  volume={33 9},
  pages={
          959-970
        }
}
Despite advances in regenerative medicine and tissue engineering, human skin substitutes remain a clear goal to achieve. Autografts remain the principal clinical option. The long-term changes in dermis, as well as its response after injuries, are not well known. Research in this field has been hindered by a lack of experimental animal models. This study analyzes the architectural dermal scaffold (collagen and elastin fibers plus fibrillin-microfibrils) changes in a model of human skin pressure… CONTINUE READING

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