Human skin carcinoma arising from kidney transplant-derived tumor cells.

@article{Verneuil2013HumanSC,
  title={Human skin carcinoma arising from kidney transplant-derived tumor cells.},
  author={Laurence Verneuil and Mariana Varna and Philippe Ratajczak and C. Di Batista Leboeuf and Louis-François Plassa and Morad Elbouchtaoui and Ph. Schneider and Wissam Sandid and Celeste Lebb{\'e} and Marie-noelle Peraldi and François Sigaux and Hugues de Th{\'e} and Anne Janin},
  journal={The Journal of clinical investigation},
  year={2013},
  volume={123 9},
  pages={
          3797-801
        }
}
Tumor cells with donor genotype have been identified in human skin cancer after allogeneic transplantation; however, the donor contribution to the malignant epithelium has not been established. Kidney transplant recipients have an increased risk of invasive skin squamous cell carcinoma (SCC), which is associated with accumulation of the tumor suppressor p53 and TP53 mutations. In 21 skin SCCs from kidney transplant recipients, we systematically assessed p53 expression and donor/recipient origin… CONTINUE READING

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