Human skeletal muscle myosin light chains analyzed by immobilized pH gradients during ontogenesis: identification of new phosphorylatable isoforms of light chain 2.

@article{Pernelle1990HumanSM,
  title={Human skeletal muscle myosin light chains analyzed by immobilized pH gradients during ontogenesis: identification of new phosphorylatable isoforms of light chain 2.},
  author={J J Pernelle and Pier Giorgio Righetti and Juan P{\'e}dro Wahrmann and B Herv{\'e}},
  journal={Electrophoresis},
  year={1990},
  volume={11 4},
  pages={325-32}
}
Previous studies using two-dimensional gel electrophoresis have described adult and fetal isoforms of skeletal muscle myosin light chains (MLC). They have also revealed an embryo-specific light chain (LC1emb), apparently absent in most adult skeletal muscles. In order to characterize more thoroughly the MLC family, we have analyzed the MLCs from human skeletal muscle at different developmental stages using a two-dimensional electrophoresis technique with an immobilized pH gradient in the first… CONTINUE READING