Human sepsis-associated Escherichia coli (SEPEC) is able to adhere to and invade kidney epithelial cells in culture

@inproceedings{Conceio2012HumanSE,
  title={Human sepsis-associated Escherichia coli (SEPEC) is able to adhere to and invade kidney epithelial cells in culture},
  author={R. A. Conceiç{\~a}o and M. Ludovico and C. L. T. Andrade and Tomomasa Yano},
  booktitle={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2012}
}
The adhesins of extraintestinal pathogenic Escherichia coli are essential for mediating direct interactions between the microbes and the host cell surfaces that they infect. Using fluorescence microscopy and gentamycin protection assays, we observed that 49 sepsis-associated E. coli (SEPEC) strains isolated from human adults adhered to and invaded Vero cells in the presence of D-mannose (100%). In addition, bacteria concentrations of approximately 2 x 10(7) CFU/mL were recovered from Vero cells… CONTINUE READING

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