Human rhinovirus 14 enters rhabdomyosarcoma cells expressing icam-1 by a clathrin-, caveolin-, and flotillin-independent pathway.

@article{Khan2010HumanR1,
  title={Human rhinovirus 14 enters rhabdomyosarcoma cells expressing icam-1 by a clathrin-, caveolin-, and flotillin-independent pathway.},
  author={Abdul Ghafoor Khan and Angela Maria Pickl-Herk and Leszek Gajdzik and Thomas C Marlovits and Renate Irmgard Roswitha Fuchs and Dieter Blaas},
  journal={Journal of virology},
  year={2010},
  volume={84 8},
  pages={
          3984-92
        }
}
Intercellular adhesion molecule 1 (ICAM-1) mediates binding and entry of major group human rhinoviruses (HRVs). Whereas the entry pathway of minor group HRVs has been studied in detail and is comparatively well understood, the pathway taken by major group HRVs is largely unknown. Use of immunofluorescence microscopy, colocalization with specific endocytic markers, dominant negative mutants, and pharmacological inhibitors allowed us to demonstrate that the major group virus HRV14 enters… CONTINUE READING

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VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 48 REFERENCES

The clathrin endocytic pathway in viral infection.

  • The EMBO journal
  • 1998
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Internalization of human rhinovirus 14 into HeLa and ICAM-1-transfected BHK cells

  • Medical Microbiology and Immunology
  • 1997
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Virus entry by macropinocytosis

  • Nature Cell Biology
  • 2009
VIEW 2 EXCERPTS