Human recombinant migration inhibitory factor activates human macrophages to kill tumor cells.

Abstract

A recombinant form of human migration inhibitory factor (rMIF) obtained from COS-1 cells transfected with MIF-specific cDNA is able to activate cultured human peripheral blood monocytes and monocyte-derived macrophages, in a dose-dependent manner to become cytotoxic for tumor cells in vitro. The cytotoxicity exhibited by macrophages treated with rMIF is… (More)

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@article{Pozzi1992HumanRM, title={Human recombinant migration inhibitory factor activates human macrophages to kill tumor cells.}, author={Luigi Pozzi and William Weiser}, journal={Cellular immunology}, year={1992}, volume={145 2}, pages={372-9} }