Human prothymocytes. Membrane properties, differentiation patterns, glucocorticoid sensitivity, and ultrastructural features

@article{Galili1980HumanPM,
  title={Human prothymocytes. Membrane properties, differentiation patterns, glucocorticoid sensitivity, and ultrastructural features},
  author={Uri Galili and Aaron Polliack and Elimelech Okon and R Leizerovitz and Haim Gamliel and A Korkesh and J G Schenkar and Gabriel Izak},
  journal={The Journal of Experimental Medicine},
  year={1980},
  volume={152},
  pages={796 - 807}
}
Thymic precursor cells (prothymocytes) comprise a large proportion of the fetal thymic cell population, but are less frequently encountered in the postnatal thymus, where they compose < 1% of the entire population. In the present study we attempted to characterize a number of properties of the prothymocytes obtained from human fetal thymic tissues after depletion of the E-rosette thymocyes on a Ficoll-Hypaque gradient. The prothymocytes are larger than the thymocytes and show a different… CONTINUE READING

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