Human protamines and the developing spermatid: their structure, function, expression and relationship with male infertility.

@article{Aoki2003HumanPA,
  title={Human protamines and the developing spermatid: their structure, function, expression and relationship with male infertility.},
  author={Vincent W. Aoki and Douglas T. Carrell},
  journal={Asian journal of andrology},
  year={2003},
  volume={5 4},
  pages={315-24}
}
During spermiogenesis, the protamine proteins play an integral role in spermatid chromatin compaction. Recent research has focused on many facets of protamine biology, including protamine gene and protein structure/function relationships, mechanisms of protamine expression regulation and involvement of the protamines in male fertility. In this paper, we review our current understanding of the structure and function of the protamine-1 (P1) and protamine-2 (P2) proteins and genes, the expression… CONTINUE READING

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