Human protamines and male infertility

@article{Khara1997HumanPA,
  title={Human protamines and male infertility},
  author={K. K. Khara and Mihaela Vlad and Mark A. Griffiths and Christopher R. J. Kennedy},
  journal={Journal of Assisted Reproduction and Genetics},
  year={1997},
  volume={14},
  pages={282-290}
}
Purpose: Our purpose was to determine the ratio of protamine 1 to protamine 2 in human spermatozoa and relate it to in vitro fertilization rates (IVF) and standard semen parameters. Methods: Couples who had been clinically diagnosed as having male-factor infertility and had undergone IVF treatment were grouped according to IVF rates and pregnancy outcome. Protamines were extracted and separated on acid urea polyacrylamide gels. The P1/P2 ratio correlation with semen parameters and IVF rates was… CONTINUE READING

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