Human prostate cancer: a direct role for oestrogens.

  title={Human prostate cancer: a direct role for oestrogens.},
  author={Luigi A. M. Castagnetta and Giuseppe Carruba},
  journal={Ciba Foundation symposium},
  pages={269-86; discussion 286-9}
We have studied the response to oestrogen and expression of oestrogen receptors in responsive LNCaP and androgen non-responsive PC3 human prostate cancer cell lines. Growth of LNCaP cells is significantly stimulated by physiological concentrations of oestradiol; this growth increase appears to be comparable to that induced by either testosterone or… CONTINUE READING