Human progenitor cells with high aldehyde dehydrogenase activity efficiently engraft into damaged liver in a novel model.

@article{Zhou2009HumanPC,
  title={Human progenitor cells with high aldehyde dehydrogenase activity efficiently engraft into damaged liver in a novel model.},
  author={Ping Zhou and Sara Hohm and Yetunde Olusanya and David A Hess and Jan A Nolta},
  journal={Hepatology},
  year={2009},
  volume={49 6},
  pages={1992-2000}
}
UNLABELLED Human cord blood stem cells (hCBSCs) have been reported to generate hepatocyte-like cells and thus hold promise for repairing damaged liver. However, the frequency of hCBSC-derived hepatocytes varies tremendously between different studies, and it is still controversial as to whether hCBSC-derived cells can transdifferentiate into hepatocytes or simply fuse to recipient hepatocytes. We used the beta-glucuronidase-deficient nonobese diabetic/severe combined immunodeficient… CONTINUE READING

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