Human prodynorphin gene generates several tissue-specific transcripts

@article{Telkov1998HumanPG,
  title={Human prodynorphin gene generates several tissue-specific transcripts},
  author={Miroslav Telkov and Thomas Geijer and Lars Terenius},
  journal={Brain Research},
  year={1998},
  volume={804},
  pages={284-295}
}
The present study analyzes the transcription of the human prodynorphin gene. Transfection experiments indicate that promoter activity for the 2.8 kb 'brain-type' human prodynorphin mRNA resides in the DNA region located 140-180 b upstream of the exon 1/intron A boundary and not 1.2 kb further upstream, as proposed by others [S. Horikawa, T. Takai, M. Toyosato, H. Takahashi, M. Noda, H. Kakidani, T. Kubo, T. Hirose, S. Tanayama, H. Hayashida, T. Miyata, S. Numa, Isolation and structural… CONTINUE READING

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