Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells

Abstract

An unusual molecular structure of the prion protein, PrPsc is found only in mammals with transmissible prion diseases. Prion protein stands for either the infectious pathogen itself or a main component of it. Recent studies suggest that autophagy is one of the major functions that keep cells alive and has a protective effect against the neurodegeneration… (More)
DOI: 10.18632/oncotarget.8802

Topics

6 Figures and Tables

Cite this paper

@inproceedings{Moon2016HumanPP, title={Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells}, author={Jihong Moon and Ju-Hee Lee and Uddin MD. Nazim and You-Jin Lee and Jae-Won Seol and Seong-kug Eo and John-hwa Lee and Sang-Youel Park}, booktitle={Oncotarget}, year={2016} }