Human population expansion and microsatellite variation.

@article{Zhivotovsky2000HumanPE,
  title={Human population expansion and microsatellite variation.},
  author={Lev A. Zhivotovsky and Leon Bennett and Anne M Bowcock and Marcus W. Feldman},
  journal={Molecular biology and evolution},
  year={2000},
  volume={17 5},
  pages={757-67}
}
Polymorphisms at di-, tri-, and tetranucleotide microsatellite loci have been analyzed in 14 worldwide populations. A statistical index of population expansion, denoted S(k), is introduced to detect historical changes in population size using the variation at the microsatellites. The index takes the value 0 at equilibrium with constant population size and is positive or negative according to whether the population is expanding or contracting, respectively. The use of S(k) requires estimation of… CONTINUE READING

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