Human polymorphonuclear neutrophil activation with arachidonic acid.

@article{Smith1987HumanPN,
  title={Human polymorphonuclear neutrophil activation with arachidonic acid.},
  author={Robert D. J. Smith and Laurel M. Sam and James M. Justen and Karen Leach and Dennis E. Van Epps},
  journal={British journal of pharmacology},
  year={1987},
  volume={91 3},
  pages={641-9}
}
The capacity of arachidonic acid (AA) to stimulate granule exocytosis from human polymorphonuclear neutrophils (PMNs) was investigated. AA induced the selected extracellular release of azurophil (myeloperoxidase, lysozyme) and specific (lysozyme, vitamin B12 binding protein) granule constituents from human PMNs in a time- and concentration-dependent manner… CONTINUE READING