Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk.

@article{Jin2011HumanPA,
  title={Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk.},
  author={Guangfu Jin and Jielin Sun and Sarah D. Isaacs and Kathleen E. Wiley and Seong-Tae Kim and L. W. Chu and Zheng Zhang and Hui Zhao and S{\'i}qun Lilly Zheng and William B Isaacs and Jianfeng Xu},
  journal={Carcinogenesis},
  year={2011},
  volume={32 11},
  pages={1655-9}
}
Long non-coding RNAs (lncRNAs), representing a large proportion of non-coding transcripts across the human genome, are evolutionally conserved and biologically functional. At least one-third of the phenotype-related loci identified by genome-wide association studies (GWAS) are mapped to non-coding intervals. However, the relationships between phenotype-related loci and lncRNAs are largely unknown. Utilizing the 1000 Genomes data, we compared single-nucleotide polymorphisms (SNPs) within the… CONTINUE READING

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