Human platelets damage Aspergillus fumigatus hyphae and may supplement killing by neutrophils.

@article{Christin1998HumanPD,
  title={Human platelets damage Aspergillus fumigatus hyphae and may supplement killing by neutrophils.},
  author={L Christin and Deborah R Wysong and Tova Meshulam and R. P. Hastey and Elizabeth R. Simons and Richard D. Diamond},
  journal={Infection and immunity},
  year={1998},
  volume={66 3},
  pages={1181-9}
}
Neutropenia is considered a significant risk factor for invasive aspergillosis but is almost always associated with concurrent thrombocytopenia. Studies determined that platelets, like neutrophils, attached to cell walls of the invasive hyphal form of Aspergillus fumigatus. Organisms were damaged as shown by loss of cell wall integrity in scanning laser confocal microscopy and release of defined hyphal surface glycoproteins. Rapid expression appearance of surface antigen CD63 and release of… CONTINUE READING
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