Human platelet supernatant promotes proliferation but not differentiation of articular chondrocytes

@article{Kaps2002HumanPS,
  title={Human platelet supernatant promotes proliferation but not differentiation of articular chondrocytes},
  author={Dr C. Kaps and Alexander Loch and Andreas Haisch and Heike Smolian and G. R. Burmester and Thomas Haeupl and Michael Sittinger},
  journal={Medical and Biological Engineering and Computing},
  year={2002},
  volume={40},
  pages={485-490}
}
The objective of the study was to evaluate the growth-promoting activity of human platelet supernanant on primary chondrocytes in comparison with fetal calf serum (FCS) supplemented cell culture medium. Furthermore, the differentiation potential of platelet supernatant was determined in three-dimensional artificial cartilage tissues of bovine articular chondrocytes. Proliferation of articular and nasal septal chondrocytes was assayed by incorporation of BrdU upon stimulation with ten different… CONTINUE READING