Human platelet P-235, a talin-like actin binding protein, binds selectively to mixed lipid bilayers.

@article{Heise1991HumanPP,
  title={Human platelet P-235, a talin-like actin binding protein, binds selectively to mixed lipid bilayers.},
  author={H W Heise and Thomas M. Bayerl and Gerhard Isenberg and Erich Sackmann},
  journal={Biochimica et biophysica acta},
  year={1991},
  volume={1061 2},
  pages={121-31}
}
The interaction of platelet talin (P-235) with mixtures of dimyristoylphosphatidylcholine (DMPC), dimyristoylphosphatidylglycerol (DMPG) and dimyristoylphosphatidylserine (DMPS) as well as with pure lipids was studied in reconstituted lipid bilayers. Incorporation of platelet talin into vesicles was achieved by self-assembly during cycles of freeze-thawing of co-dispersions containing vesicles and the purified protein. The yield of protein incorporation as a function of lipid composition was… CONTINUE READING
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