Human plasma metabolomics in age-related macular degeneration (AMD) using nuclear magnetic resonance spectroscopy

@inproceedings{Lans2017HumanPM,
  title={Human plasma metabolomics in age-related macular degeneration (AMD) using nuclear magnetic resonance spectroscopy},
  author={In{\^e}s La{\'i}ns and Daniela Rezende Duarte and Ant{\'o}nio Sousa Barros and Ana Sofia Martins and Jo{\~a}o Quadrado Gil and John Bernard Miller and Marco Frederico Marques and T{\^a}nia Mesquita and Ivana K. Kim and Maria da Luz Cachulo and Demetrios G Vavvas and Isabel Marques Carreira and J. N. Murta and Rufino Silva and Joan W Miller and Deeba Husain and Ana M Gil},
  booktitle={PloS one},
  year={2017}
}
PURPOSE To differentiate the plasma metabolomic profile of patients with age related macular degeneration (AMD) from that of controls, by Nuclear Magnetic Resonance (NMR) spectroscopy. METHODS Two cohorts (total of 396 subjects) representative of central Portugal and Boston, USA phenotypes were studied. For each cohort, subjects were grouped according to AMD stage (early, intermediate and late). Multivariate analysis of plasma NMR spectra was performed, followed by signal integration and… CONTINUE READING
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