Human plasma fibronectin potentiates the mitogenic activity of platelet-derived growth factor and complements its wound healing effects.

@article{Larivire2003HumanPF,
  title={Human plasma fibronectin potentiates the mitogenic activity of platelet-derived growth factor and complements its wound healing effects.},
  author={Beno{\^i}t Larivi{\`e}re and Mich{\`e}le Rouleau and Sylvain Picard and Andr{\'e} D. Beaulieu},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  year={2003},
  volume={11 1},
  pages={79-89}
}
Integrin-mediated cell adhesion and growth factor stimuli are both required for optimal control of cell proliferation. In the context of skin injury, cell-derived fibronectin and platelet-derived growth factor play important roles in the stimulation of cell proliferation and migration, activities that are crucial to the healing process. To assess the ability of exogenously supplied plasma-derived fibronectin to stimulate wound repair and to study its ability to cooperate with platelet-derived… CONTINUE READING

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