Human placenta-derived neurospheres are susceptible to transformation after extensive in vitro expansion


The cancer stem cell model links neoplastic cells with normal stem cell biology, but little is known on how normal stem cells are transformed into cancer stem cells. To investigate the processes underlying the transformation of normal stem cells we developed in vitro a cancer stem cell model from human amniotic and chorionic placenta membranes. In this… (More)
DOI: 10.1186/scrt444


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