Human pathologies associated with defective RNA transport and localization in the nervous system.

@article{Dahm2007HumanPA,
  title={Human pathologies associated with defective RNA transport and localization in the nervous system.},
  author={R. J. Dahm and Paolo Macchi},
  journal={Biology of the cell},
  year={2007},
  volume={99 11},
  pages={649-61}
}
RNA localization is emerging as an important process to restrict certain proteins to specific subcellular domains and thus spatially control the expression of genes within cells. It is used, for instance, to compartmentalize the developing embryo during early embryogenesis. The localization of RNA also plays important roles later during development, such as in asymmetric cell divisions, cell migration and the outgrowth and pathfinding of axons and dendrites. In differentiated cells, it serves… CONTINUE READING

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