Human parechovirus central nervous system infections in southern California children.

@article{Felsenstein2014HumanPC,
  title={Human parechovirus central nervous system infections in southern California children.},
  author={Susanna Felsenstein and Shangxin Yang and Natalie Eubanks and Edwin R. Sobrera and John Grimm and Grace M Aldrovandi},
  journal={The Pediatric infectious disease journal},
  year={2014},
  volume={33 4},
  pages={e87-91}
}
BACKGROUND Human parechoviruses (hPeV) are increasingly recognized as significant etiological agents for meningoencephalitis especially in young children, but testing of cerebrospinal fluid (CSF) for hPeV by PCR is not routinely performed. METHODS We used real-time reverse transcriptase PCR for detection of serotypes 1-6 in CSF samples of 440 children who underwent a lumbar puncture to exclude an infectious etiology of their clinical presentation. We then compared the prevalence and clinical… CONTINUE READING
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