Human papillomavirus type 16 E5 protein induces expression of beta interferon through interferon regulatory factor 1 in human keratinocytes.

@article{Muto2011HumanPT,
  title={Human papillomavirus type 16 E5 protein induces expression of beta interferon through interferon regulatory factor 1 in human keratinocytes.},
  author={Valentina Muto and Emilia Stellacci and Angelo Giuseppe Lamberti and Edvige Perrotti and Aurora Carrabba and Giovanni Matera and Marco Sgarbanti and Angela Battistini and Maria Carla Liberto and Alfredo Foc{\`a}},
  journal={Journal of virology},
  year={2011},
  volume={85 10},
  pages={5070-80}
}
Crucial steps in high-risk human papillomavirus (HR-HPV)-related carcinogenesis are the integration of HR-HPV into the host genome and loss of viral episomes. The mechanisms that promote cervical neoplastic progression are, however, not clearly understood. During HR-HPV infection, the HPV E5 protein is expressed in precancerous stages but not after viral integration. Given that it has been reported that loss of HPV16 episomes and cervical tumor progression are associated with increased… CONTINUE READING
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Effects of human papillomavirus type 16 E5 deletion mutants on epithelial morphology: functional characterization of each transmembrane domain

  • S Barbaresi
  • J. Gen. Virol
  • 2010
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