Human papillomavirus positivity predicts favourable outcome for squamous carcinoma of the tonsil.

@article{Li2003HumanPP,
  title={Human papillomavirus positivity predicts favourable outcome for squamous carcinoma of the tonsil.},
  author={Wei Li and Carol H. Thompson and Christopher J O'brien and Edward B. McNeil and Richard A Scolyer and Yvonne E Cossart and Michael J Veness and Donald Murray Walker and G. James Morgan and Barbara R. Rose},
  journal={International journal of cancer},
  year={2003},
  volume={106 4},
  pages={553-8}
}
Mutations in the p53 and retinoblastoma (pRb) pathways associated with the use of tobacco and alcohol are common in squamous cell carcinoma (SCC) of the head and neck. Cell cycle proteins are also affected by human papillomavirus (HPV), which may also have an aetiological role in cancers at particular sites, most notably the tonsil. Attempts to identify prognostic molecular markers in head and neck cancers have met with conflicting results, but few studies have been undertaken with tumours of… CONTINUE READING

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