Human papillomavirus modifies the prognostic significance of T stage and possibly N stage in tonsillar cancer.

@article{Hong2013HumanPM,
  title={Human papillomavirus modifies the prognostic significance of T stage and possibly N stage in tonsillar cancer.},
  author={Angela M. Hong and Arthur L. Martin and Bruce Konrad Armstrong and Cheok Soon Lee and Deanna Jones and Mark D. Chatfield and Min-fang Zhang and Gerald B. Harnett and Janet Clark and Michael Elliott and Chris G. Milross and Robert Ian Smee and June F. Corry and Chang Liu and Sandro Virgilio Porceddu and Kasturi Vaska and Michael J Veness and Glenn H Morgan and Gerald B Fogarty and David Veivers and Guy Rees and Barbara A Rose},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2013},
  volume={24 1},
  pages={
          215-9
        }
}
BACKGROUND Despite the association with more advanced nodal stage, patients with human papillomavirus (HPV) positive oropharyngeal cancers have better outcomes. We examined whether the HPV can modify the effect of known prognostic factors in tonsillar cancer. PATIENTS AND METHODS A total of 489 patients from 10 centres were followed up for recurrence or death for a median of 3.2 years. Determinants of the rate of locoregional recurrence, death from tonsillar cancer and overall survival were… CONTINUE READING
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