Human papillomavirus is a favourable prognostic factor in cancer of unknown primary in the head and neck region and in hypopharyngeal cancer.

@article{Sivars2016HumanPI,
  title={Human papillomavirus is a favourable prognostic factor in cancer of unknown primary in the head and neck region and in hypopharyngeal cancer.},
  author={Lars Sivars and Cinzia Bersani and Nathalie Gr{\"u}n and Torbj{\"o}rn Ramqvist and Eva Munck-Wikland and Christian von Buchwald and Tina Dalianis},
  journal={Molecular and clinical oncology},
  year={2016},
  volume={5 6},
  pages={671-674}
}
Human papillomavirus (HPV), in addition to smoking and alcohol, is a cause of oropharyngeal squamous cell carcinoma (OPSCC), particularly of the tonsils and base of the tongue (TSCC and BOTSCC, respectively). Moreover, HPV-positive TSCC and BOTSCC are associated with a better outcome compared with their HPV-negative counterparts (80 vs. 40% 3-year disease-free survival rate, respectively) and their incidence has increased in several countries. Recently, accumulating evidence of HPV in a… CONTINUE READING