Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity.

@article{Gillison2004HumanPH,
  title={Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity.},
  author={Maura L. Gillison},
  journal={Seminars in oncology},
  year={2004},
  volume={31 6},
  pages={744-54}
}
There is currently sufficient evidence to conclude that human papillomavirus (HPV) plays a role in the pathogenesis of a distinct subset of head and neck squamous cell cancers (HNSCC), particularly tonsillar cancers. There is a strong and consistent association between high-risk HPV types, specifically HPV16, a known human carcinogen, and these distinctive oropharyngeal cancers with molecular characteristics indicative of viral oncogene function. Risk for HPV-HNSCC is increased by certain… CONTINUE READING
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There is a strong and consistent association between high - risk HPV types , specifically HPV16 , a known human carcinogen , and these distinctive oropharyngeal cancers with molecular characteristics indicative of viral oncogene function .
There is a strong and consistent association between high - risk HPV types , specifically HPV16 , a known human carcinogen , and these distinctive oropharyngeal cancers with molecular characteristics indicative of viral oncogene function .
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