Human papillomavirus and head and neck cancer: a systematic review and meta‐analysis

@article{Hobbs2006HumanPA,
  title={Human papillomavirus and head and neck cancer: a systematic review and meta‐analysis},
  author={C G L Hobbs and Jonathan A. C. Sterne and Michael Bailey and Robert Simon Heyderman and Martin A. Birchall and S J Thomas},
  journal={Clinical Otolaryngology},
  year={2006},
  volume={31}
}
It has been suggested that the link between human papillomavirus (HPV) and head and neck squamous cell carcinoma (HNSCC) is specific to carcinoma of the tonsil. [...] Key Method We systematically reviewed studies that tested for HPV16 exposure in anatomically defined sites in the head and neck and a control group. The association between HPV16 and cancer was strongest for tonsil (OR: 15.1, 95% CI: 6.8-33.7), intermediate for oropharynx (OR: 4.3, 95% CI: 2.1-8.9) and weakest for oral (OR: 2.0, 95% CI: 1.2-3.4…Expand
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