Human papillomavirus and cervical cancer
- Medicine, BiologyJournal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
HPV testing in the secondary prevention of cervical cancer is clinically valuable in triaging low-grade cytological abnormalities and is also more sensitive than cytology as a primary screening.
Human Papillomavirus and Cervical Cancer
- Medicine, BiologyCervical Cancer - A Global Public Health Treatise [Working Title]
HPV plays a major role in the development of cervical cancer, but histological types have different relationships with HPV genotypes, and HPV vaccination provides a direct benefit to both men and women by providing safe protection against cancers that may result from persistent HPV infection.
[Human papillomavirus infection. Pathology and molecular pathology].
- Medicine, BiologyDer Pathologe
The Ständige Impfkommission, the German standing committee on immunizations, has recommended the prophylactic use of vaccines against the two most frequent HR-HPV genotypes, HPV-16 and HPV-18, in women age 12-17 years before first sexual intercourse.
Human papillomaviruses as therapeutic targets in human cancer.
- Biology, MedicineJournal of clinical oncology : official journal of the American Society of Clinical Oncology
It has been estimated that there will be no measurable decline of HPV-associated cervical cancers before 2040, and therapeutic efforts to combat high-risk HPV- associated disease remain of critical importance.
Role of HPV16 E1 in cervical carcinogenesis
- BiologyFrontiers in Cellular and Infection Microbiology
A possible mechanism by which E1 drives cell proliferation and oncogenesis will be discussed, and the emerging role of HPV E1 in cervical carcinogenesis is emphasized.
Human papillomavirus infection and its role in the pathogenesis of anal cancer
- Medicine, Biology
Studies are currently in progress to determine whether treatment of anal HSIL reduces the risk of cancer among HIV-infected men and women, and to define the molecular events associated with progression from HSIL to cancer.
HPV and Cervical Cancer
The very high negative predictive value of HPV testing speaks in favor of its use in screening of cervical cancer to reduce the mortality related to this neoplasia particularly in developing countries.
Human Papillomavirus in the HIV-Infected Host: Epidemiology and Pathogenesis in the Antiretroviral Era
- Medicine, BiologyCurrent HIV/AIDS Reports
Men and women with human immunodeficiency virus (HIV) infection are at high risk of HPV-related malignancies and should be screened for cervical HSIL and cancer, and HIV-infected men and women should be considered for anal screening programs.
Prevention of Complications from Human Papillomavirus Infection in the HIV-Infected Individual
- Medicine, Biology
Ongoing work to optimize screening for both cervical and anal HSIL to prevent cancer at these sites, as well as increasing uptake of prophylactic HPV vaccines, are currently the best options to decrease HPV-related complications in PLWH.
SHOWING 1-10 OF 226 REFERENCES
The carcinogenicity of human papillomavirus types reflects viral evolution.
- Biology, MedicineVirology
Molecular biology of human papillomavirus infection and cervical cancer.
- Medicine, BiologyClinical science
High-risk HPV DNA is found in almost all cervical cancers (>99.7%), with HPV16 being the most prevalent type in both low-grade disease and cervical neoplasia, and the pattern of viral gene expression in low- grade cervical lesions resembles that seen in productive warts caused by other HPV types.
Human papillomavirus type 18 and rapidly progressing cervical intraepithelial neoplasia
- MedicineThe Lancet
Viral load of human papilloma virus 16 as a determinant for development of cervical carcinoma in situ: a nested case-control study
- MedicineThe Lancet
The epidemiology of human papillomavirus infections.
- Biology, MedicineJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Chapter 2: Natural history of anogenital human papillomavirus infection and neoplasia.
- Medicine, BiologyJournal of the National Cancer Institute. Monographs
This chapter suggests promising areas of future epidemiologic research on human papillomavirus (HPV) and anogenital cancer, organized around our understanding of cervical carcinogenesis. The major…
A 2-year prospective study of human papillomavirus persistence among women with a cytological diagnosis of atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion.
- Medicine, BiologyThe Journal of infectious diseases
Although virtually all HPV infections clear within 2 years, the remaining infections have a high potential for persistence and, by implication, progression to precancer and cancer.
Relationships of human papillomavirus type, qualitative viral load, and age with cytologic abnormality.
- Medicine, BiologyCancer research
The lack of evident severe abnormalities associated with HPV18 and related HPV types might have implications for screening for poorly detected glandular and alpha7-related lesions, as well as the potential of the full range of anogenital HPV genotypes to induce cytopathic effects.
New markers for cervical dysplasia to visualise the genomic chaos created by aberrant oncogenic papillomavirus infections.
- Biology, MedicineEuropean journal of cancer