Human papillomavirus E7 serology and association with p16 immunohistochemistry in squamous cell carcinoma of the head and neck.

@article{Khanal2015HumanPE,
  title={Human papillomavirus E7 serology and association with p16 immunohistochemistry in squamous cell carcinoma of the head and neck.},
  author={Sujita Khanal and Joongho Joh and Amy M. Kwon and Maryam Zahin and Cesar Augusto Perez and Neal Edward Dunlap and Craig L Silverman and Paul Albert Tennant and Kevin L Potts and Goetz Haus Kloecker and Jeffrey Milton Bumpous and Shin-je Ghim and Alfred Bennett Jenson and Rebecca Ann Redman},
  journal={Experimental and molecular pathology},
  year={2015},
  volume={99 2},
  pages={335-40}
}
BACKGROUND Human papillomavirus (HPV)-positive oropharyngeal cancer is associated with improved survival and treatment response as compared to HPV-negative cancers. P16 overexpression is widely accepted as a surrogate marker for HPV positivity. METHODS A total of 92 serum samples from 75 head and neck squamous cell carcinoma (HNSCC) patients were examined… CONTINUE READING