Human papillomavirus E6 and E7 oncoproteins as risk factors for tumorigenesis

@article{Ganguly2009HumanPE,
  title={Human papillomavirus E6 and E7 oncoproteins as risk factors for tumorigenesis},
  author={Niladri Ganguly and S. P. Parihar},
  journal={Journal of Biosciences},
  year={2009},
  volume={34},
  pages={113-123}
}
Human papillomavirus (HPV) is small, double-stranded DNA virus that infects mucosal and cutaneous epithelial tissue. HPV is sexually transmitted and the viral DNA replicates extrachromosomally. The virus is non-enveloped and has an icosahedral capsid. There are approximately 118 types of HPV, which are characterized as high-risk or lowrisk types. High-risk HPVs cause malignant transformation while the low-risk ones cause benign warts and lesions. The expression of E6 and E7 is normally… Expand
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