Human papillomavirus DNA in cervical carcinoma—correlation with clinical data and influence on prognosis
@article{Ikenberg1994HumanPD, title={Human papillomavirus DNA in cervical carcinoma—correlation with clinical data and influence on prognosis}, author={H. Ikenberg and W. Sauerbrei and U. Schottm{\"u}ller and C. Spitz and A. Pfleiderer}, journal={International Journal of Cancer}, year={1994}, volume={59} }
Human papillomavirus (HPV) is a main factor in cervical carcinogenesis. However, data on the correlation of HPV with clinical features and the prognosis of cervical carcinoma remain controversial. The HPV status (positivity, type, copy number) in unfixed tissue specimens of 205 primary invasive cervical carcinomas was determined by Southern blot hybridization. A correlation with comprehensive clinical and histopathologic data and long‐time survival was evaluated. HPV DNA was detected in 73% of… CONTINUE READING
Topics from this paper
38 Citations
Human papillomavirus genotype as a major determinant of the course of cervical cancer.
- Medicine
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology
- 1998
- 147
Prognostic value of pre-treatment human papilloma virus DNA status in cervical cancer.
- Medicine
- Gynecologic oncology
- 2018
- 7
Human papilloma virus (HPV) DNA associated with prognosis of cervical cancer after radiotherapy.
- Medicine
- International journal of radiation oncology, biology, physics
- 2002
- 64
Human papillomavirus type 18: association with poor prognosis in early stage cervical cancer.
- Medicine
- Journal of the National Cancer Institute
- 1996
- 116
Low initial human papilloma viral load implicates worse prognosis in patients with uterine cervical cancer treated with radiotherapy.
- Medicine
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology
- 2009
- 51
Prognostic value of HPV DNA status in cervical cancer before treatment: a systematic review and meta-analysis.
- Medicine
- Oncotarget
- 2017
- 19
- PDF
Human Papillomavirus Type 18: Association With Poor Prognosis in Early Stage Cervical Cancer
- Medicine
- 1996
- 79
- PDF
References
SHOWING 1-10 OF 28 REFERENCES
Possible prognostic significance of human papillomavirus type in cervical cancer.
- Medicine
- Gynecologic oncology
- 1988
- 124
Human Papillomavirus Genotype as a Prognostic Indicator in Carcinoma of the Uterine Cervix
- Medicine
- Obstetrics and gynecology
- 1989
- 122
Increased age and mortality associated with cervical carcinomas negative for human papillomavirus RNA
- Medicine
- The Lancet
- 1991
- 140
Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA
- Medicine
- The Lancet
- 1990
- 268
Prognostic significance of the presence of human papillomavirus DNA in patients with invasive carcinoma of the cervix
- Medicine
- Cancer
- 1989
- 71
Human papillomaviruses and cervical cancer: analysis of histopathologic features associated with different viral types.
- Biology, Medicine
- Human pathology
- 1988
- 115
The prevalence of human papillomavirus type 16 and 18 DNA in cervical cancer in different age groups: a study on the incidental cases of cervical cancer in Norway in 1983.
- Medicine
- Gynecologic oncology
- 1991
- 13
HPV 16 DNA IN NORMAL AND MALIGNANT CERVICAL EPITHELIUM: IMPLICATIONS FOR THE AETIOLOGY AND BEHAVIOUR OF CERVICAL NEOPLASIA
- Biology, Medicine
- The Lancet
- 1987
- 189
Alterations of the p53 gene in human primary cervical carcinoma with and without human papillomavirus infection.
- Biology, Medicine
- Cancer research
- 1992
- 172
A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1983
- 1,749
- PDF