Human papillomavirus DNA in cervical carcinoma—correlation with clinical data and influence on prognosis

@article{Ikenberg1994HumanPD,
  title={Human papillomavirus DNA in cervical carcinoma—correlation with clinical data and influence on prognosis},
  author={H. Ikenberg and W. Sauerbrei and U. Schottm{\"u}ller and C. Spitz and A. Pfleiderer},
  journal={International Journal of Cancer},
  year={1994},
  volume={59}
}
  • H. Ikenberg, W. Sauerbrei, +2 authors A. Pfleiderer
  • Published 1994
  • Medicine
  • International Journal of Cancer
  • Human papillomavirus (HPV) is a main factor in cervical carcinogenesis. However, data on the correlation of HPV with clinical features and the prognosis of cervical carcinoma remain controversial. The HPV status (positivity, type, copy number) in unfixed tissue specimens of 205 primary invasive cervical carcinomas was determined by Southern blot hybridization. A correlation with comprehensive clinical and histopathologic data and long‐time survival was evaluated. HPV DNA was detected in 73% of… CONTINUE READING
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