Human papillomavirus 16 and head and neck squamous cell carcinoma.

@article{Furniss2007HumanP1,
  title={Human papillomavirus 16 and head and neck squamous cell carcinoma.},
  author={Constance Sloane Furniss and Michael D Mcclean and Judith F. Smith and Janine T. Bryan and Heather H. Nelson and Edwards S Peters and Marshall Roy Posner and John Ross Clark and Ellen A. Eisen and Karl T. Kelsey},
  journal={International journal of cancer},
  year={2007},
  volume={120 11},
  pages={2386-92}
}
Evidence suggests that human papillomavirus (HPV)16 seropositivity reflects past HPV16 exposure and is associated with risk for head and neck squamous cell carcinoma (HNSCC). Our objectives were to test the hypothesis that HPV16 seropositivity is associated with risk for HNSCC, to correlate HPV16 seropositivity with HPV16 tumor DNA, and to correlate HPV16 seropositivity and HPV16 DNA with sexual history and patient survival. In a case-control study of approximately 1,000 individuals, we… CONTINUE READING