Human papillomavirus 16 E6 polymorphisms in cervical lesions from different European populations and their correlation with human leukocyte antigen class II haplotypes.

@article{Zehbe2001HumanP1,
  title={Human papillomavirus 16 E6 polymorphisms in cervical lesions from different European populations and their correlation with human leukocyte antigen class II haplotypes.},
  author={Ingeborg Zehbe and Ruth Tachezy and Joannis Mytilineos and Gianfranco Voglino and Iva Mikyskov{\'a} and Hajo Delius and Antonella Marongiu and Lutz Gissmann and Erik Wilander and Massimo Tommasino},
  journal={International journal of cancer},
  year={2001},
  volume={94 5},
  pages={711-6}
}
Infection with high-risk human papillomavirus (HPV) is necessary for the development of a cervical lesion, but only a fraction of precursor lesions progress to cancer. Additional factors, other than HPV type per se, are likely to increase the probability for progression. Intratype genome variations have been reported to be associated with viral persistence and the development of a major cervical disease. We have recently shown that the prevalence of specific HPV16-E6 variants in invasive… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

Similar Papers

Loading similar papers…