Human papillomavirus-16 E5 protein: oncogenic role and therapeutic value

  title={Human papillomavirus-16 E5 protein: oncogenic role and therapeutic value},
  author={Niladri Ganguly},
  journal={Cellular Oncology},
Human papillomavirus (HPV) is a non-enveloped, double-stranded DNA virus. HPV infection occurs through sexual route, and the virus infects mucosal and cutaneous epithelial cells. Inside the cell, the viral DNA replicates extrachromosomally. HPV is the major cause of cervical cancer worldwide. HPVs infecting mucosal epithelial cells are sub-grouped into low-risk or high-risk by virtue of them causing benign warts or cancer, respectively. The early oncoproteins of HPV, namely E4, E5, E6 and E7… CONTINUE READING
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