Human papillomavirus (HPV) type 6 and 16 DNA sequences in bronchial squamous cell carcinomas demonstrated by in situ DNA hybridization

@article{Syrjnen2007HumanP,
  title={Human papillomavirus (HPV) type 6 and 16 DNA sequences in bronchial squamous cell carcinomas demonstrated by in situ DNA hybridization},
  author={K. Syrj{\"a}nen and S. Syrj{\"a}nen and J. Kellokoski and J. K{\"a}rj{\"a} and R. M{\"a}ntyj{\"a}rvi},
  journal={Lung},
  year={2007},
  volume={167},
  pages={33-42}
}
A series of 131 routinely processed, paraffin-embedded biopsy specimens derived from the same number of patients with a bronchial squamous cell carcinoma were analyzed using in situ DNA-hybridization technique with a probe cocktail containing35S-labeled human papillomavirus (HPV) DNA of types 6, 11, 16, 18, and 30. The 12 carcinomas shown to contain HPV DNA by the probe cocktail were subjected to in situ hybridization with the specific HPV DNA probes applied separately under high stringency… Expand
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