Human osteoblast cultures from osteoporotic and healthy bone: biochemical markers and cytokine expression in basal conditions and in response to 1,25(OH)2D3.


The development of methods to culture bone cells has enhanced in vitro studies and allowed researchers to investigate bone cell metabolism in healthy tissue and in various different bone diseases. Greater knowledge of cultures of pathologic bone tissue-derived osteoblasts may be helpful in performing in vitro experiments that test biomaterials and therapies… (More)