Human organic anion transporter 3 gene is regulated constitutively and inducibly via a cAMP-response element.

@article{Ogasawara2006HumanOA,
  title={Human organic anion transporter 3 gene is regulated constitutively and inducibly via a cAMP-response element.},
  author={Ken Ogasawara and Tomohiro Terada and Jun-ichi Asaka and Toshiya Katsura and Ken-ichi Inui},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2006},
  volume={319 1},
  pages={317-22}
}
Human organic anion transporter (OAT) 3 (SLC22A8) is localized to the basolateral membranes of renal tubular epithelial cells and plays a critical role in the excretion of anionic compounds. We previously reported that interindividual variation in the OAT3 mRNA level corresponded to interindividual differences in the rate of renal excretion of cefazolin. However, there is little information available on the molecular mechanisms regulating the gene expression of OAT3. Therefore, in the present… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Regulation of Expression of Renal Organic Anion Transporters OAT1 and OAT3 in a Model of Ischemia/Reperfusion Injury.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology • 2015

The hURAT1 rs559946 polymorphism and the incidence of gout in Han Chinese men.

Scandinavian journal of rheumatology • 2014
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 28 references

Molecular physiology of renal organic anion transporters.

American journal of physiology. Renal physiology • 2006
View 2 Excerpts

Similar Papers

Loading similar papers…