Human oocytes and preimplantation embryos express mRNA for growth hormone receptor.

@article{Menezo2003HumanOA,
  title={Human oocytes and preimplantation embryos express mRNA for growth hormone receptor.},
  author={Yves J R Menezo and Said El Mouatassim and Martine Chavrier and Edouard J. Servy and Bernard Nicolet},
  journal={Zygote},
  year={2003},
  volume={11 4},
  pages={293-7}
}
Human genetic expression of growth hormone receptor (GHR) gene was qualitatively analysed using reverse transcription polymerase chain reaction (RT-PCR) in cumulus cells, immature germinal vesicle (GV) and mature metaphase II (MII) stage oocytes and preimplantation human embryos. The transcripts encoding GHR were detected in cumulus cells and also in naked oocytes, either mature or not. In this case, a nested PCR is needed, as for early embryo preimplantation stages, before genomic activation… CONTINUE READING

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