Human oligodendrocytes are not sensitive to complement. A study of CD59 expression in the human central nervous system.


BACKGROUND One or more components of the oligodendrocyte-myelin unit are the target of immune attack in multiple sclerosis. The role of complement in this process has been suggested by the demonstration in vitro that rat oligodendrocytes are sensitive to lysis by Ab-independent complement attack, partly because of a lack of the complement regulatory protein… (More)


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