Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation

@inproceedings{Farges2015HumanOC,
  title={Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation},
  author={J. P. Farges and Aur{\'e}lie Bellanger and Maxime Ducret and Elisabeth Aubert-Foucher and B{\'e}atrice Richard and Brigitte Alliot-Licht and Françoise Bleicher and Florence Carrouel},
  booktitle={Front. Physiol.},
  year={2015}
}
The penetration of cariogenic oral bacteria into enamel and dentin during the caries process triggers an immune/inflammatory response in the underlying pulp tissue, the reduction of which is considered a prerequisite to dentinogenesis-based pulp regeneration. If the role of odontoblasts in dentin formation is well known, their involvement in the antibacterial response of the dental pulp to cariogenic microorganisms has yet to be elucidated. Our aim here was to determine if odontoblasts produce… CONTINUE READING