Human ocular aldehyde dehydrogenase isozymes: distribution and properties as major soluble proteins in cornea and lens.

@article{King1998HumanOA,
  title={Human ocular aldehyde dehydrogenase isozymes: distribution and properties as major soluble proteins in cornea and lens.},
  author={Gareth King and Roger S. Holmes},
  journal={The Journal of experimental zoology},
  year={1998},
  volume={282 1-2},
  pages={12-7}
}
Human aldehyde dehydrogenase isozymes (ALDHs; EC 1.2.1.3) exhibit very high levels of activity in anterior eye tissues. Human corneal ALDH1 and ALDH3 isozymes are present as major soluble proteins (3% and 5%, respectively, of corneal soluble protein) and may play major roles in protecting the cornea against ultraviolet radiation (UVR)-induced tissue damage, as well as contributing directly to ultraviolet B (UV-B) photoreception. The human lens exhibits high levels of ALDH1 activity (1-2% of… CONTINUE READING

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