Human neural stem cell transplantation provides long-term restoration of neuronal plasticity in the irradiated hippocampus.

@article{Acharya2015HumanNS,
  title={Human neural stem cell transplantation provides long-term restoration of neuronal plasticity in the irradiated hippocampus.},
  author={Munjal M. Acharya and Susanna Rosi and Timothy D. Jopson and Charles L. Limoli},
  journal={Cell transplantation},
  year={2015},
  volume={24 4},
  pages={
          691-702
        }
}
For the majority of CNS malignancies, radiotherapy provides the best option for forestalling tumor growth, but is frequently associated with debilitating and progressive cognitive dysfunction. Despite the recognition of this serious side effect, satisfactory long-term solutions are not currently available and have prompted our efforts to explore the potential therapeutic efficacy of cranial stem cell transplants. We have demonstrated that intrahippocampal transplantation of human neural stem… CONTINUE READING
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