• DOI:10.1039/B417651K
Corpus ID: 15853187

Human neural stem cell growth and differentiation in a gradient-generating microfluidic device.

@article{Chung2005HumanNS,
  title={Human neural stem cell growth and differentiation in a gradient-generating microfluidic device.},
  author={B. Chung and L. Flanagan and S. Rhee and P. Schwartz and A. Lee and E. Monuki and N. L. Jeon},
  journal={Lab on a chip},
  year={2005},
  volume={5 4},
  pages={
          401-6
        }
}

• B. Chung, L. Flanagan, +4 authors N. L. Jeon
• Published 2005
• Biology, Medicine
• Lab on a chip

This paper describes a gradient-generating microfluidic platform for optimizing proliferation and differentiation of neural stem cells (NSCs) in culture. Microfluidic technology has great potential to improve stem cell (SC) cultures, whose promise in cell-based therapies is limited by the inability to precisely control their behavior in culture. Compared to traditional culture tools, microfluidic platforms should provide much greater control over cell microenvironment and rapid optimization of… Expand

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